NAMPT antibody

Catalog No. ABIN7116869

The Mouse Monoclonal anti-NAMPT antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect NAMPT in samples from Human, Rat and Mouse.

Quick Overview for NAMPT antibody (ABIN7116869)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 2G6

Product Details anti-NAMPT Antibody

Purpose: NAMPT antibody

Purification: protein A+G purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nicotinamide phosphoribosyltransferase

Isotype: IgG2b

Application Details

Application Notes: WB: 1:1000-1:4000, IHC: 1:50-1:500, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: NAMPT

Background:

Synonyms: Nicotinamide phosphoribosyltransferase (NAmPRTase, Nampt)|Pre-B-cell colony-enhancing factor 1 (Pre-B cell-enhancing factor)|Visfatin|NAMPT|PBEF|PBEF1

Background: Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Molecular Weight: 52 kDa

Gene ID: 10135

UniProt: P43490